E-locus

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MC1R

This protein is a cell membrane bound receptor that can be activated by α-MSH or inhibited by the agouti protein. Once activated it mediates eumelanin production via cAmp. Some mutations of the MC1R protein result in a constitutively active receptor and thus hightened eumelanin production.

Alleles

Extended Black

Birchen

Wheaten

Duckwing (wildtype)

Brown as in Partridge